Annuaire - Biomedical Sciences  
 
 
 
 
 
 
   
 
 
 
 
   
  EA-2224
   
  EA-2224
Speciality: Immunoloy and molecular biology.
Director : Pr. C- J LARSEN
Phone Labo: 33 (0)5 49 45 49 56
e-mail : c.j.larsen@chu-poitiers.fr
 

EA-2224 Immunoloy and molecular biology. 19 researchers.

Research topics:

Immunology (team of JC Lecron, MCU-PH, JM Gombert, PUPH))

- Physio-pathological studies of certain cytokins (IL6, IL10) during inflammations and cardiac pathologies.
- Physio-pathological analysis of the hyper IgD syndrom.
- Analysis of the human NK T cell populations in oncogenic processes.

Microbiology (équipes J Frere PU à SFA, JL Fauchere, PUPH)

Genetic and antigenic diversity in helicobacter pylori.

- Role of the mutS2 gene.
- Study of the variations during an experimental infection.
- Antigenic markers.

Genetic and cancer (équipes CJ Larsen, PUPH, A Brizard, PUPH, J Roche PU SFA)

- Study of the tumor suppressor gene p14ARF and its interaction with the type I topoisomerase.
- Regulation of the expression of the P53 family (p53, p73, p63) in astroglial tumors.
- Chronic myeloid leukemia: study of the transcription level of p14ARF et p16INK4a the course of the illness and during treatment.


Techniques and equipment of interest:

Cell culture, cell fractioning techniques. Cell flow cytometry
Quantitative RT-PCR
Mass spectometry

   
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