Synthesis & reactivity of natural substances. 20 researchers.
Research topics:
1. Synthesis and transformation of natural products and of products with a pharmacological activity.
- Superacids : Superacid, Fluoration, Alkaloids, Hypervalent Iodine, Hypnotic (J.C. Jacquesy & M. P. Jouannetaud)
- Synthesis of Biomolecules: anticancerous, cytotoxic agents, enzyme inhibitors (histone deacetylase, phosphatase), prodrugs, Antifongic, Anti-inflammatory, Antidiabetic (J.P. Gesson).
2. Organic geochemistry: Study of the organic matter in soil & sediments (A. Ambles).
3. Methodology and synthesis of pharmacologically active molecules. New approaches using micro-waves, parallel chemistry, chemistry of sugars, of amino acids and other natural substances; synthesis of new products, morphinoids, pyrroles (G. Bashiardes).
Techniques and equipment of interest
Multi-stage organic synthesis.
Separation & structural analysis techniques of complex organic mixtures and organic compounds.
Strategic methods to study of biomacromolecules.
Use of soil for the remediation & treatment of solid-waste and waste water.
FTIR spectometer, mass spectometer, AVANCE DPX300 NMR spectrometer, HPLC,
Polarimetry, Pyrolyser
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